Effects of creatine monohydrate supplementation on simulated soccer performance

Purpose: To determine the effects of acute short-term creatine (Cr) supplementation on physical performance during a 90-min soccer-specific performance test. Methods: A double-blind, placebo-controlled experimental design was adopted during which 16 male amateur soccer players were required to consume 20 g/d Cr for 7 d or a placebo. A Ball-Sport Endurance and Speed Test (BEAST) comprising measures of aerobic (circuit time), speed (12- and 20-m sprint), and explosive-power (vertical jump) abilities performed over 90 min was performed presupplementation and postsupplementation. Results: Performance measures during the BEAST deteriorated during the second half relative to the first for both Cr (1.2–2.3%) and placebo (1.0–2.2%) groups, indicating a fatigue effect associated with the BEAST. However, no significant differences existed between groups, suggesting that Cr had no performance-enhancing effect or ability to offset fatigue. When effect sizes were considered, some measures (12-m sprint, –0.53 ± 0.69; 20-m sprint, –0.39 ± 0.59) showed a negative tendency, indicating chances of harm were greater than chances of benefit. Conclusions: Acute short-term Cr supplementation has no beneficial effect on physical measures obtained during a 90-min soccer-simulation test, thus bringing into question its potential as an effective ergogenic aid for soccer players

Changing patterns of religious affiliation, church attendance and marriage across five areas of Europe since the early 1980s: trends and associations

This study draws on three waves of the European Values Survey (conducted between 1981 and 1984, between 1989 and 1993, and between 1999 and 2004) across five countries for which full data are available (Great Britain, Italy, the Netherlands, Northern Ireland, Spain, and Sweden) in order to address five research questions. Question one examined changes in religious affiliation. Across all five countries, the proportions of the non-affiliated increased. Question two examined changes in church attendance. Across all five countries, the proportions of the non-attenders increased. Question three examined changes in marital status. Across all five countries the proportions of the population checking the category 'married' declined, although in Spain the decline was marginal. Question four examined the association between religious affiliation and being married. The religious affiliated were more likely to be married than the non-affiliated. Question five examined the association between church attendance and being married. Weekly attenders were more likely to be married than the non-attenders. Overall these data support the close association between religion and marriage across five European countries (where there are very different religious climates) and support the hypothesis that changing religious values and changing family values go hand-in-hand

Does "Fight or Flight" Need Updating?

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Tissue-specific regulation of sirtuin and nicotinamide adenine dinucleotide biosynthetic pathways identified in C57Bl/6 mice in response to high-fat feeding

Funding: The Scottish Government's Rural and Environment Science and Analytical Services Division.Peer reviewedPostprin

Preventing post-disaster PTSD: Watch for autonomic signs

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The human fear-circuitry and fear-induced fainting in healthy individuals The paleolithic-threat hypothesis

The Paleolithic-Threat hypothesis reviewed here posits that habitual efferent fainting can be traced back to fear-induced allelic polymorphisms that were selected into some genomes of anatomically, mitochondrially, and neurally modern humans (Homo sapiens sapiens) in the Mid-Paleolithic because of the survival advantage they conferred during periods of inescapable threat. We posit that during Mid-Paleolithic warfare an encounter with “a stranger holding a sharp object” was consistently associated with threat to life. A heritable hard- wired or firm-wired (prepotentiated) predisposition to abruptly increase vagal tone and collapse flaccidly rather than freeze or attempt to flee or fight in response to an approaching sharp object, a minor injury, or the sight of blood, polymorphism for the hemodynamically “paradoxical” flaccid- immobility in response to these stimuli may have increased some non-combatants’ chances of survival. This is consistent with the unusual age and sex pattern of fear-induced fainting. The Paleolithic-Threat hypothesis also predicts a link to various hypo-androgenic states (e.g. low dehydroxyepiandrosterone-sulfate. We offer five predictions testable via epidemiological, clinical, and ethological/primatological methods. The Paleolithic-Threat hypothesis has implications for research in the aftermath of man-made disasters, such as terrorism against civilians, a traumatic event in which this hypothesis predicts epidemics of fear-induced faintin